High-risk Sexual Behavior for HIV Acquisition is Associated with Gut Microbial Community in Men Who Have Sex with Men - Takeaways - MDSpire

High-risk Sexual Behavior for HIV Acquisition is Associated with Gut Microbial Community in Men Who Have Sex with Men

  • By

  • Kangjie Li

  • Tian Liu

  • Xiaohua Zhong

  • Jiaxiu Liu

  • Pinyi Chen

  • Bing Lin

  • Xiaoni Zhong

  • September 16, 2025

  • 0 min

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  • 1

    Gut dysbiosis is linked to higher HIV acquisition risk in HIV sero-negative men who have sex with men (MSM).

  • 2

    High-risk MSM exhibited greater gut microbiota diversity compared to low-risk participants, as indicated by Shannon and Simpson indices.

  • 3

    Beta diversity analysis revealed significant differences in gut microbiota composition between high-risk and low-risk MSM groups.

  • 4

    Specific microbial taxa, such as Barnesiella and Roseburia, showed differential abundance between high-risk and low-risk MSM.

  • 5

    The study suggests that gut microbiota may serve as a target for HIV prevention strategies among MSM.

Original Source(s)

High-risk Sexual Behavior for HIV Acquisition is Associated with Gut Microbial Community in Men Who Have Sex with Men

  • by Kangjie Li, Tian Liu, Xiaohua Zhong, Jiaxiu Liu, Pinyi Chen, Bing Lin, Xiaoni Zhong

  • September 16, 2025

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