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Social Vulnerability May Contribute to Disparities in Ovarian Cancer Survival
Neighborhood vulnerability was associated with poorer survival among women with epithelial ovarian cancer, with a stronger association among Black women.
Black women with epithelial ovarian cancer had 45% higher adjusted odds of mortality compared to White women in a study of 2,544 patients.
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The median Social Vulnerability Index (SVI) was significantly higher for Black women (0.78) than for White women (0.48), indicating greater social vulnerability.
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Residence in high-SVI areas was linked to 20% higher adjusted odds of mortality compared to low-SVI areas across the overall cohort.
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Black women in high-SVI areas had 77% higher adjusted odds of mortality compared to White women in low-SVI areas, highlighting racial disparities.
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The study found that 16% of the excess relative risk of mortality was due to the interaction between race and SVI, with 40% through pathways involving SVI.