Cardiovascular Effects of Aggressive Blood Pressure Management in Individuals With and Without Metabolic Dysfunction-Associated Fatty Liver Disease: A Post Hoc Analysis of the CRHCP Study - Takeaways - MDSpire

Cardiovascular Effects of Aggressive Blood Pressure Management in Individuals With and Without Metabolic Dysfunction-Associated Fatty Liver Disease: A Post Hoc Analysis of the CRHCP Study

  • By

  • Songyue Liu

  • Yangzhi Yin

  • Hongmei Yang

  • Lufan Sun

  • Jun Wang

  • Ying Zhou

  • Lin Guan

  • Liying Xing

  • Ziyi Xie

  • Ning Ye

  • Chuan Yang

  • Wei Miao

  • Shiyu Zhou

  • Yao Yu

  • Zhi Li

  • Xiangyu Tan

  • Caiyu Zhang

  • Chenhua He

  • Yueting Liu

  • Yifei Chen

  • Guozhe Sun

  • Xiaofan Guo

  • March 4, 2026

  • 0 min

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  • 1

    Metabolic dysfunction-associated fatty liver disease (MAFLD) affects nearly 30% of the global population and is linked to increased cardiovascular disease risk.

  • 2

    Current hypertension guidelines lack specific recommendations for blood pressure management in individuals with MAFLD, despite its association with cardiovascular risks.

  • 3

    The CRHCP trial analyzed the effects of intensive blood pressure control on cardiovascular outcomes in individuals with and without MAFLD.

  • 4

    The study included 29,624 participants, with 12,912 diagnosed with MAFLD, assessing the efficacy of targeting blood pressure below 130/80 mmHg.

  • 5

    Findings from this analysis highlight the need for further research to establish evidence-based blood pressure management strategies for MAFLD patients.

Original Source(s)

Cardiovascular Effects of Aggressive Blood Pressure Management in Individuals With and Without Metabolic Dysfunction-Associated Fatty Liver Disease: A Post Hoc Analysis of the CRHCP Study

  • by Songyue Liu, Yangzhi Yin, Hongmei Yang, Lufan Sun, Jun Wang, Ying Zhou, Lin Guan, Liying Xing, Ziyi Xie, Ning Ye, Chuan Yang, Wei Miao, Shiyu Zhou, Yao Yu, Zhi Li, Xiangyu Tan, Caiyu Zhang, Chenhua He, Yueting Liu, Yifei Chen, Guozhe Sun, Xiaofan Guo

  • March 4, 2026

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