Lymph node involvement influences prognosis in resectable non-metastatic solid pseudopapillary tumors of the pancreas: a SEER-based population study - Takeaways - MDSpire

Lymph node involvement influences prognosis in resectable non-metastatic solid pseudopapillary tumors of the pancreas: a SEER-based population study

  • By

  • Vincenzo D’Ambra

  • Claudio Ricci

  • Laura Alberici

  • Carlo Ingaldi

  • Marco Fichera

  • Stefano Togni

  • Riccardo Casadei

  • February 13, 2026

  • 0 min

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  • 1

    Solid Pseudopapillary Tumors (SPTs) of the pancreas are rare neoplasms with generally favorable prognosis after surgical resection.

  • 2

    The study analyzed 293 patients with resectable, non-metastatic SPTs using data from the SEER database to identify prognostic factors.

  • 3

    Key findings indicated that older age, positive lymph nodes, and high lymph-node ratio significantly correlated with worse overall survival.

  • 4

    The overall 5-year survival rate for the cohort was 96.2%, highlighting the generally favorable outcomes for patients with SPTs.

  • 5

    Multivariate analysis confirmed that age, lymph node involvement, and tumor location are independent predictors of prognosis in SPTs.

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