Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review - Takeaways - MDSpire

Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review

  • By

  • Norbert Dosa

  • Intouch Limvaree

  • Camila Bonin Pinto

  • Faddi Saleh Velez

  • Zalan Kaposzta

  • Zsofia Szarvas

  • Zachary C. Pope

  • Anna Csiszar

  • Wajeeha Razaq

  • Ryan D. Nipp

  • Andriy Yabluchanskiy

  • Peter Mukli

  • June 2, 2026

  • 0 min

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  • 1

    Chemotherapy-related cognitive impairment (CRCI) significantly affects memory, attention, and executive function in cancer survivors.

  • 2

    This systematic review analyzed 17 studies on non-pharmacological interventions aimed at improving cognitive outcomes in CRCI.

  • 3

    Mild cognitive improvements were observed across various interventions, including brain stimulation and complementary therapies.

  • 4

    Study limitations included small sample sizes, lack of control groups, and biases, affecting the validity of findings.

  • 5

    The review highlights the need for large-scale randomized controlled trials to better assess non-pharmacological strategies for CRCI.

Original Source(s)

Chemotherapy-related cognitive impairment and non-pharmacological interventions targeting the nervous system: a systematic review

  • by Norbert Dosa, Intouch Limvaree, Camila Bonin Pinto, Faddi Saleh Velez, Zalan Kaposzta, Zsofia Szarvas, Zachary C. Pope, Anna Csiszar, Wajeeha Razaq, Ryan D. Nipp, Andriy Yabluchanskiy, Peter Mukli

  • June 2, 2026

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