Real-world comparison of Rezūm® water vapor therapy and transurethral resection of the prostate using a pragmatic composite definition of procedural success - Takeaways - MDSpire

Real-world comparison of Rezūm® water vapor therapy and transurethral resection of the prostate using a pragmatic composite definition of procedural success

  • By

  • Teresa Pina-Vaz

  • Alberto Costa Silva

  • Margarida Henriques

  • Hugo Antunes

  • Pedro Dias

  • Carlos Martins-Silva

  • João Alturas Silva

  • Afonso Morgado

  • February 25, 2026

  • 0 min

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  • 1

    Rezūm® water vapor therapy is a minimally invasive treatment for benign prostatic enlargement (BPE) that aims to reduce lower urinary tract symptoms (LUTS).

  • 2

    Transurethral resection of the prostate (TURP) remains the gold standard for surgical management of BPE-related LUTS, but minimally invasive options like Rezūm are gaining traction.

  • 3

    The study compared procedural success between Rezūm and TURP using a new composite definition that includes symptom improvement, safety, and preservation of sexual function.

  • 4

    Patients treated with Rezūm experienced more medication side effects and longer catheterization duration compared to those treated with TURP.

  • 5

    At one month post-procedure, Rezūm patients had higher rates of storage symptoms and acute urinary retention compared to TURP patients.

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