Eight-year disease-free survival in clear cell adenocarcinoma of the urethra with surgery alone: a case report and literature review

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A 39-year-old woman with clear cell adenocarcinoma of the urethra was treated with surgery alone and has survived 8 years without recurrence.
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Imaging revealed a 5.1 cm urethral mass invading the bladder and vagina, with a clinical stage of T3N2M0 confirmed by urine cytology.
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The patient underwent laparoscopic radical cystectomy, lymph node dissection, and cutaneous ureterostomy, with no adjuvant therapy administered.
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Postoperative pathology confirmed clear cell adenocarcinoma at stage T3N0M0, with no evidence of lymph node metastasis.
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Follow-up through January 2025 showed no tumor recurrence, although the patient experienced recurrent febrile episodes diagnosed as pyelonephritis.

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