Pharmacologic treatment strategies and association with major neonatal outcomes for patent ductus arteriosus in preterm infants - Takeaways - MDSpire

Pharmacologic treatment strategies and association with major neonatal outcomes for patent ductus arteriosus in preterm infants

  • By

  • Ercan Tutak

  • Nimet Cındık

  • Eser Doğan

  • Yunus Emre Ayhan

  • Onur Özer

  • July 9, 2026

  • 0 min

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  • 1

    Patent ductus arteriosus (PDA) is prevalent in preterm infants and is linked to various neonatal complications.

  • 2

    This study evaluated pharmacologic treatment strategies for PDA in preterm infants and their association with major neonatal outcomes.

  • 3

    76 preterm infants were included, with treatment strategies being ibuprofen only, paracetamol only, or sequential therapy.

  • 4

    The composite outcome of bronchopulmonary dysplasia and/or mortality occurred in 51.3% of infants, with no significant differences across treatment groups.

  • 5

    Gestational age was identified as the strongest independent predictor of bronchopulmonary dysplasia and/or mortality.

Original Source(s)

Pharmacologic treatment strategies and association with major neonatal outcomes for patent ductus arteriosus in preterm infants

  • by Ercan Tutak, Nimet Cındık, Eser Doğan, Yunus Emre Ayhan, Onur Özer

  • July 9, 2026

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