Clinical study on the value of TyG index combined with systemic immune-inflammation index for screening hospitalized patients with type 2 diabetic kidney disease

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The study evaluated the combined utility of the TyG index and SII for identifying diabetic kidney disease in hospitalized T2DM patients.
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A total of 335 hospitalized T2DM patients were analyzed, with 175 diagnosed with diabetic kidney disease and 160 without.
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The final prediction model achieved an AUC of 0.850, indicating strong screening performance for diabetic kidney disease.
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Optimal cut-off values were determined as TyG >10.03 and lgSII >2.76, with a sensitivity of 74.3% and specificity of 85.0%.
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The study suggests that the TyG and SII combination could serve as a low-cost tool for early risk stratification of diabetic kidney disease.

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