Sensitivity and specificity of speckle tracking echocardiography for coronary artery disease: a systematic review and meta-analysis - Takeaways - MDSpire
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Diagnostic Accuracy of Speckle Tracking Echocardiography in Identifying Coronary Artery Disease: A Systematic Review and Meta-Analysis

  • By

  • Linping Xu

  • Haoqi Xu

  • Zhi Pan

  • Ruizhong Ye

  • August 28, 2026

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  • 1

    The systematic review assessed the diagnostic performance of myocardial strain parameters from speckle-tracking echocardiography for coronary artery disease.

  • 2

    Forty studies with 5,296 participants were included, revealing pooled sensitivity of 77.3% and specificity of 75.0% for speckle-tracking echocardiography.

  • 3

    Global longitudinal strain (GLS) showed sensitivity of 78.6% and specificity of 76.3%, while global area strain (GAS) had the highest sensitivity at 83.3%.

  • 4

    Exercise stress STE demonstrated greater sensitivity compared to dobutamine stress or no-stress protocols, with recovery-phase measurements showing promising results.

  • 5

    The overall certainty of evidence was rated low due to high risk of bias, indirectness, and imprecision in the studies reviewed.

Original Source(s)

Sensitivity and specificity of speckle tracking echocardiography for coronary artery disease: a systematic review and meta-analysis

  • by Linping Xu, Haoqi Xu, Zhi Pan, Ruizhong Ye

  • August 28, 2026

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