England Expands Newborn SMA Screening

National rollout of genetic testing strengthens the role of laboratory services in early diagnosis

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England will expand newborn genetic screening for spinal muscular atrophy (SMA) through the national heel-prick screening program.
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The initiative aims to identify affected infants before symptoms develop, enhancing treatment effectiveness.
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Laboratory testing for SMA screening is expected to begin in October 2026, three months earlier than initially planned.
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The program will generate real-world evidence through a £4.1 million evaluation funded by the National Institute for Health and Care Research.
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Implementation will continue through 2027, ensuring all newborn screening laboratories in England offer the SMA test.

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