Development and Implementation of an AI System for Generating Clinical Urine Drug Test Sign-Outs - Takeaways - MDSpire

Development and Implementation of an AI System for Generating Clinical Urine Drug Test Sign-Outs

  • By

  • Nathan Laha

  • Michael Keebaugh

  • Hsuan-Chieh Liao

  • Bright Amankwaa

  • Olumuyiwa Adesoye

  • Abed Pablo

  • William S. Phipps

  • Andrew N. Hoofnagle

  • Geoffrey S. Baird

  • Patrick C. Mathias

  • Brody H. Foy

  • June 23, 2026

  • 0 min

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  • 1

    Urine drug tests (UDTs) are utilized in various clinical settings to monitor medication adherence, especially in patients with substance use disorders.

  • 2

    Complex UDT cases may require consultation with clinical chemists, which can increase turnaround times and operational costs.

  • 3

    The study developed an AI tool using nongenerative machine-learning to generate preliminary interpretations of UDTs, enhancing toxicology services.

  • 4

    The AI tool achieved expert-level accuracy and reduced sign-out time when integrated into the clinical UDT workflow.

  • 5

    Data for the study were collected from UWM's health record system, focusing on substances detectable under 2024 testing protocols.

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