Analysis of latent profiles of stressors and their influencing factors in patients with breast cancer undergoing postoperative chemotherapy: a mixed-methods study - Takeaways - MDSpire
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Investigation of Hidden Stressor Profiles and Contributing Factors in Breast Cancer Patients Receiving Postoperative Chemotherapy: A Mixed-Methods Approach

  • By

  • Jingjing Chen

  • Tiantian Yang

  • Xiaoling Yan

  • August 21, 2026

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  • 1

    A study investigated stress experiences among 232 breast cancer patients receiving postoperative chemotherapy using a mixed-methods approach.

  • 2

    Four latent stress profiles were identified: Low-stress Adaptive, Moderate-High Physio-Psychological Distress, High Medical Concerns, and High-Stress Across Domains.

  • 3

    Age was found to have a protective effect against moderate-high and high-stress profiles, while advanced clinical stage increased likelihood of high medical concerns.

  • 4

    Qualitative interviews revealed three central themes: multiple stressors, depletion of psychological resources, and the dual impact of external support systems.

  • 5

    Over 70% of participants reported moderate-to-high stress, highlighting the need for targeted psychosocial support based on identified stress profiles.

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