Mesonephric-like adenocarcinoma as an unexpected histological result after fertility saving procedure for presumed adenomyosis: a case report - Takeaways - MDSpire

Mesonephric-like adenocarcinoma as an unexpected histological result after fertility saving procedure for presumed adenomyosis: a case report

  • By

  • Vojtěch Lukavec

  • Filip Frühauf

  • Zdenka Lisa

  • Jan Galko

  • Pavel Dundr

  • Michal Mara

  • June 5, 2026

  • 0 min

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  • 1

    A 41-year-old woman was misdiagnosed with diffuse adenomyosis, presenting with primary infertility and heavy menstrual bleeding.

  • 2

    Histopathological examination revealed unexpected mesonephric-like adenocarcinoma after planned cytoreductive surgery for adenomyosis.

  • 3

    The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and received chemotherapy with immunotherapy.

  • 4

    Mesonephric-like adenocarcinoma can mimic adenomyosis, highlighting the need for thorough evaluation of atypical myometrial lesions.

  • 5

    This case emphasizes the risk of diagnostic pitfalls in reproductive medicine, particularly in patients with suspected adenomyosis.

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