Infective Endocarditis in People Who Inject Drugs—A 5-Year Follow-up: “I’ve Seen the Needle and the Damage Done” - Takeaways - MDSpire

Infective Endocarditis in People Who Inject Drugs—A 5-Year Follow-up: “I’ve Seen the Needle and the Damage Done”

  • By

  • Mika Halavaara

  • Veli-Jukka Anttila

  • Asko Järvinen

  • February 5, 2025

  • 0 min

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  • 1

    The study analyzed long-term outcomes of infective endocarditis (IE) in injecting drug users (PWID) compared to non-PWID adults.

  • 2

    Fifteen PWID experienced a new IE episode within five years, significantly higher than five in the non-PWID group (OR, 4.65; P = .003).

  • 3

    Five-year all-cause mortality was 18.7% in PWID with IE, compared to 13.3% in non-PWID, indicating poor long-term survival.

  • 4

    Injection drug use, female gender, and higher comorbidity index were independent factors associated with death during follow-up.

  • 5

    The findings highlight the need for improved addiction treatment efforts to enhance long-term outcomes for PWID with IE.

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