Traditional Chinese medicine in sepsis-associated PICS: potential immunometabolic mechanisms and translational perspectives - Takeaways - MDSpire
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Exploring the Role of Traditional Chinese Medicine in Sepsis-Related PICS: Insights into Immunometabolic Mechanisms and Clinical Implications

  • By

  • Pochen Li

  • Fangyu Yu

  • Er Hong

  • Yan Wu

  • Danxia Ge

  • Qianping Zhang

  • Yujiao Li

  • Yang Wu

  • August 17, 2026

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  • 1

    Persistent inflammation, immunosuppression, and catabolism syndrome (PICS) significantly contributes to long-term morbidity in sepsis survivors.

  • 2

    Traditional Chinese medicine (TCM) is being explored as a complementary approach in critical care for managing sepsis-related PICS.

  • 3

    Xuebijing injection has shown associations with improved short-term clinical outcomes and reduced inflammatory markers in sepsis patients.

  • 4

    Existing studies primarily focus on the acute phase of sepsis, lacking sufficient evidence on TCM's role during the recovery phase associated with PICS.

  • 5

    Methodological heterogeneity and variability in diagnostic definitions hinder the interpretation and generalizability of current findings on TCM in PICS.

Original Source(s)

Traditional Chinese medicine in sepsis-associated PICS: potential immunometabolic mechanisms and translational perspectives

  • by Pochen Li, Fangyu Yu, Er Hong, Yan Wu, Danxia Ge, Qianping Zhang, Yujiao Li, Yang Wu

  • August 17, 2026

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