Psychosocial stressors prior to Down Syndrome Regression Disorder: findings from two referral clinics - Takeaways - MDSpire

Psychosocial stressors prior to Down Syndrome Regression Disorder: findings from two referral clinics

  • By

  • María del Carmen Ortega

  • Felipe Ortuño

  • Diego Real de Asúa

  • July 7, 2026

  • 0 min

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  • 1

    The study examined psychosocial stressors preceding Down Syndrome Regression Disorder (DSRD) in adolescents and adults at two specialized clinics.

  • 2

    91% of individuals diagnosed with DSRD experienced at least one adverse psychosocial stressor within six months before symptom onset.

  • 3

    The most common stressors identified were bereavement or illness of a close person (35%) and separation or displacement of a significant figure (32%).

  • 4

    Initial assessments revealed social withdrawal (100%), psychomotor slowing (97%), and loss of previously acquired abilities (94%) as the most frequent symptoms.

  • 5

    The study highlights the need for systematic characterization of psychosocial stressors in relation to DSRD, although it does not establish causality.

Original Source(s)

Psychosocial stressors prior to Down Syndrome Regression Disorder: findings from two referral clinics

  • by María del Carmen Ortega, Felipe Ortuño, Diego Real de Asúa

  • July 7, 2026

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