Nutrition protocols improve caloric adequacy in critically Ill children: a systematic review and meta-analysis - Takeaways - MDSpire

Nutrition protocols improve caloric adequacy in critically Ill children: a systematic review and meta-analysis

  • By

  • Yan Wang

  • Jia Wang

  • Xiao Sun

  • Baolian Yao

  • Fang Guo

  • Yan Shi

  • Nida Naeem

  • July 14, 2026

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  • 1

    Malnutrition is prevalent among critically ill children in the PICU, leading to adverse outcomes such as prolonged mechanical ventilation and increased mortality.

  • 2

    Structured nutritional protocols significantly improve caloric adequacy, with a pooled mean difference of +21.98% in caloric delivery among critically ill pediatric patients.

  • 3

    The study included nine studies with 1,992 children across six countries, demonstrating substantial heterogeneity in caloric delivery outcomes.

  • 4

    Both nurse-led and non-nurse-led nutritional protocols improved caloric delivery without significant differences in effectiveness between the two.

  • 5

    The findings support the adoption of standardized feeding protocols to enhance nutritional care in PICUs globally.

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