Unique Case of Malignant Phyllodes Tumor in the Breast Accompanied by Epithelial Carcinoma and Chondrosarcomatous Differentiation

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A 57-year-old female was diagnosed with a malignant phyllodes tumor exhibiting low-grade ductal carcinoma in situ and chondrosarcomatous differentiation.
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Malignant phyllodes tumors are rare, constituting 10-20% of cases, and are characterized by stromal atypia and the presence of malignant heterologous elements.
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The tumor presented as a 6.0 cm palpable mass, with imaging revealing a heterogeneous mass classified as BI-RADS V, indicating a high suspicion for malignancy.
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Post-surgery, the patient received adjuvant chemotherapy but discontinued due to severe side effects, and follow-up showed no signs of recurrence or metastasis.
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The case highlights the diagnostic challenges of phyllodes tumors and the need for extensive histopathological sampling for accurate classification and management.

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