The gut microbiota in colorectal cancer: role in cytokine regulation, intestinal immune barrier dysfunction

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Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality, influenced by gut microbiota.
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Dysbiosis of the gut microbiota can lead to immune dysregulation, chronic inflammation, and contribute to CRC progression.
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Gut microorganisms interact with colonic epithelial cells and immune cells, affecting tumor immunity and inflammatory responses.
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The gut microbiota's composition can be altered by environmental factors, impacting host health and disease states.
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Emerging therapeutic strategies targeting the microbiota–immune axis may offer new approaches for CRC diagnosis and treatment.

Frontiers In Oncology

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