Non-invasive ventilation in severe acute respiratory failure complicating Madelung’s disease: a case series and management review - Takeaways - MDSpire

Non-invasive ventilation in severe acute respiratory failure complicating Madelung’s disease: a case series and management review

  • By

  • Bruno Gomes

  • Antonio M. Esquinas

  • Fares N. Alwajeeh

  • June 4, 2026

  • 0 min

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  • 1

    Madelung's disease complicates acute respiratory failure management due to difficult airway risks from cervical lipomatosis.

  • 2

    Non-invasive ventilation (NIV) was successfully used as a primary strategy for managing severe ARF in two patients with Madelung's disease.

  • 3

    Both patients avoided endotracheal intubation, highlighting NIV's potential as a life-saving approach in high-risk scenarios.

  • 4

    Complications included bilateral pneumothoraxes in one patient, necessitating careful management and adjustment of NIV settings.

  • 5

    Systematic screening for obstructive sleep apnea is crucial for optimizing outcomes in patients with Madelung's disease and ARF.

Original Source(s)

Non-invasive ventilation in severe acute respiratory failure complicating Madelung’s disease: a case series and management review

  • by Bruno Gomes, Antonio M. Esquinas, Fares N. Alwajeeh

  • June 4, 2026

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