Three-Dimensional Systolic Dyssynchrony Index in Real-Time as a Predictor of Pacing-Related Left Ventricular Dysfunction and Cardiomyopathy - Takeaways - MDSpire

Three-Dimensional Systolic Dyssynchrony Index in Real-Time as a Predictor of Pacing-Related Left Ventricular Dysfunction and Cardiomyopathy

  • By

  • Moustafa Dawood

  • Hoda Abdelgawad

  • Aly Aboelhoda

  • Moataz Zaki

  • April 27, 2026

  • 0 min

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  • 1

    Chronic right ventricular pacing can lead to left ventricular dysfunction due to mechanical dyssynchrony and abnormal electrical activation.

  • 2

    Pacing-induced ventricular dysfunction (PIVD) is common and can progress to pacing-induced cardiomyopathy (PICM), significantly impacting patient outcomes.

  • 3

    Traditional risk factors for pacing-induced dysfunction lack predictive accuracy, highlighting the need for better assessment tools.

  • 4

    The systolic dyssynchrony index (SDI) from real-time three-dimensional echocardiography offers a comprehensive measure of LV mechanical dyssynchrony.

  • 5

    This study aims to evaluate the incidence of PIVD and PICM and the predictive role of SDI shortly after pacemaker implantation.

Original Source(s)

Three-Dimensional Systolic Dyssynchrony Index in Real-Time as a Predictor of Pacing-Related Left Ventricular Dysfunction and Cardiomyopathy

  • by Moustafa Dawood, Hoda Abdelgawad, Aly Aboelhoda, Moataz Zaki

  • April 27, 2026

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