Neurobiological mechanisms of olfactory dysfunction: a ten-year bibliometric and visualization analysis - Takeaways - MDSpire

Neurobiological mechanisms of olfactory dysfunction: a ten-year bibliometric and visualization analysis

  • By

  • Yuxin Zhu

  • Yutian Chen

  • Genki Izumoji

  • Siying Qu

  • Donghai Wu

  • Huiqin Chu

  • Yixiang Wang

  • Haiju Sun

  • Xiaoyu Li

  • May 13, 2026

  • 0 min

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  • 1

    Olfactory dysfunction (OD) is increasingly recognized in neurodegenerative diseases and COVID-19, with a prevalence of approximately 22% in the general population.

  • 2

    The USA leads in research output on OD mechanisms, with significant contributions from the University of California System and author Thomas Hummel.

  • 3

    Key research topics include COVID-19, Parkinson’s disease, inflammation, and odorant receptors, indicating current trends in OD studies.

  • 4

    The study identified 14 interventional clinical trials focusing on pharmacological and non-pharmacological approaches to address OD.

  • 5

    Research on OD is shifting from broad observations to detailed molecular mechanisms, emphasizing the role of inflammation and neuroregeneration.

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