Hypertrophic Cardiomyopathy and the Likelihood of Cardiac Arrest Outside a Hospital Setting

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Hypertrophic cardiomyopathy (HCM) has a prevalence of 1 in 500 and has increased in Denmark over the past two decades.
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SCD remains a risk in HCM patients due to the disease's unpredictable nature, despite advancements in treatment and preventive care.
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The study aimed to investigate the long-term risk of out-of-hospital cardiac arrest (OHCA) in HCM patients compared to matched controls.
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Data for the study were collected from nationwide registers in Denmark, covering a period from June 2001 to December 2022.
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A nested case-control study was conducted to identify covariates associated with OHCA in patients diagnosed with HCM.

Jama Network Open

by Rasmus Bork Dinesen, Deepthi Rajan, Christian Torp-Pedersen, Niels Risum, Peder Emil Warming, Jacob Tfelt-Hansen
April 29, 2026

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