Association of cancer-related cytokines and mitochondrial DNA alterations in hepatocellular carcinoma patients and HIV-positive individuals in Ghana - Takeaways - MDSpire

Association of cancer-related cytokines and mitochondrial DNA alterations in hepatocellular carcinoma patients and HIV-positive individuals in Ghana

  • By

  • James Odame Aboagye

  • Ruth Ayanful-Torgby

  • Lei Zhou

  • Prince Peter Wormenor

  • Vincent Ganu

  • Kenneth Tachi

  • Bernard Nii Akrashie Attoh

  • Miriam Mensah

  • Timothy Kuuguu

  • Sedzro Kojo Mensah

  • George Boateng Kyei

  • Elijah Paintsil

  • November 11, 2025

  • 0 min

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  • 1

    People living with HIV (PLWH) face an increased risk of non-AIDS-defining cancers, including hepatocellular carcinoma (HCC).

  • 2

    The incidence of HCC is rising among PLWH, particularly those aged 50 and older, with prevalence rates significantly higher in sub-Saharan Africa.

  • 3

    Cytokines play a crucial role in chronic inflammation, which is linked to the development and progression of HCC in PLWH.

  • 4

    This study aims to compare cytokine levels and mitochondrial DNA alterations between PLWH and individuals with HCC without HIV in Ghana.

  • 5

    Understanding cytokine secretion patterns may enhance screening and treatment strategies for HCC in PLWH.

Original Source(s)

Association of cancer-related cytokines and mitochondrial DNA alterations in hepatocellular carcinoma patients and HIV-positive individuals in Ghana

  • by James Odame Aboagye, Ruth Ayanful-Torgby, Lei Zhou, Prince Peter Wormenor, Vincent Ganu, Kenneth Tachi, Bernard Nii Akrashie Attoh, Miriam Mensah, Timothy Kuuguu, Sedzro Kojo Mensah, George Boateng Kyei, Elijah Paintsil

  • November 11, 2025

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