Could Psychedelic Drugs Relieve Cancer Pain? - Takeaways - MDSpire

Could Psychedelic Drugs Relieve Cancer Pain?

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  • October 24, 2025

  • 6 min

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  • 1

    Roswell Park's Palliative Care team investigates psilocybin's potential to alleviate both physical and psychological cancer pain.

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    Psilocybin interacts with serotonin, acts as an anti-inflammatory, and alleviates pain by reducing anxiety and stress.

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    The upcoming clinical trial will explore micro-dosing psilocybin's effects on pain, anxiety, and opioid requirements.

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    Patients will also receive meaning-based therapy to help alleviate distress associated with cancer.

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    The study aims to address the psychological aspects of pain, an area lacking effective tools in current palliative care.

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