Alopecia Associated with Isoniazid in Cases of Isoniazid-Monoresistant Pulmonary Tuberculosis - Takeaways - MDSpire

Alopecia Associated with Isoniazid in Cases of Isoniazid-Monoresistant Pulmonary Tuberculosis

  • By

  • Emine Afşin

  • Şeref Özkara

  • Fatma Ceren Gökdemir

  • January 31, 2026

  • 0 min

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  • 1

    Alopecia is a rare adverse drug reaction associated with antituberculosis treatment, particularly in drug-resistant tuberculosis cases.

  • 2

    The case presented involves a 22-year-old woman who developed isoniazid-induced alopecia during treatment for pulmonary tuberculosis.

  • 3

    Isoniazid was discontinued after alopecia onset, leading to hair regrowth within one month, confirming its role as the causative agent.

  • 4

    Drug resistance testing revealed isoniazid monoresistance, necessitating a revised treatment plan without isoniazid.

  • 5

    Management of adverse drug reactions during antituberculosis treatment may require drug discontinuation and substitution with alternative regimens.

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