Risk of drug-related aggression in pediatric populations: a pharmacovigilance analysis using the FAERS database - Takeaways - MDSpire

Risk of drug-related aggression in pediatric populations: a pharmacovigilance analysis using the FAERS database

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The study analyzed 7,959 pediatric reports from FAERS to identify drugs associated with aggression in children.
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Thirty-one drugs were linked to aggression, with the highest signals found for ebastine and perampanel.
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Aggression signals were more pronounced in younger children and females, with median time-to-onset varying by drug.
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Drugs primarily associated with aggression included nervous system and respiratory agents, with montelukast having the highest case volume.
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The findings highlight the need for updated regulatory labeling and increased clinical vigilance regarding pediatric drug safety.

Frontiers In Pediatrics

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Frontiers In Pediatrics

Frontiers In Psychiatry

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