Post-intracerebral hemorrhage depression comorbid with obstructive sleep apnea and REM sleep behavior disorder: a case report and literature review - Takeaways - MDSpire

Post-intracerebral hemorrhage depression comorbid with obstructive sleep apnea and REM sleep behavior disorder: a case report and literature review

  • By

  • Panpan Li

  • Bidan Zhang

  • Huihua Li

  • Jingjing Sun

  • June 30, 2026

  • 0 min

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  • 1

    A 63-year-old male developed post-stroke depression after an intracerebral hemorrhage, with no improvement from standard antidepressant treatment.

  • 2

    Polysomnography confirmed comorbid severe obstructive sleep apnea hypopnea syndrome and rapid eye movement sleep behavior disorder in the patient.

  • 3

    The patient received continuous positive airway pressure therapy for obstructive sleep apnea, followed by individualized pharmacotherapy for rapid eye movement sleep behavior disorder.

  • 4

    Improvement in sleep architecture and respiratory events led to significant remission of depressive and anxiety symptoms in the patient.

  • 5

    The case highlights the importance of identifying and managing sleep disorders in patients with post-stroke depression to enhance treatment efficacy.

Original Source(s)

Post-intracerebral hemorrhage depression comorbid with obstructive sleep apnea and REM sleep behavior disorder: a case report and literature review

  • by Panpan Li, Bidan Zhang, Huihua Li, Jingjing Sun

  • June 30, 2026

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