Inflammatory bowel diseases in the elderly population: epidemiology, long-term disease course, surgery rates, and biological use—data from the Veszprem county cohort between 1977 and 2020 - Takeaways - MDSpire

Inflammatory bowel diseases in the elderly population: epidemiology, long-term disease course, surgery rates, and biological use—data from the Veszprem county cohort between 1977 and 2020

  • By

  • Dorottya Angyal

  • Lorant Gonczi

  • Fruzsina Balogh

  • Panu Wetwittayakhlang

  • Petra A Golovics

  • Tunde Pandur

  • Gyula David

  • Zsuzsanna Erdelyi

  • Istvan Szita

  • Akos Ilias

  • Laszlo Lakatos

  • Peter L Lakatos

  • January 6, 2025

  • 0 min

Share

  • 1

    Elderly-onset inflammatory bowel diseases (EO IBD) represent 6.1% of Crohn's disease and 13.4% of ulcerative colitis patients in the Veszprem cohort.

  • 2

    Biological therapy exposure was significantly lower in EO Crohn's disease patients compared to adult-onset patients, while exposure in EO ulcerative colitis was similar.

  • 3

    Early surgery rates within one year of diagnosis were higher in EO Crohn's disease patients at 27.6% compared to 15.6% in adult-onset patients.

  • 4

    Overall surgery rates for resective surgery in Crohn's disease and colectomy in ulcerative colitis were similar between EO and adult-onset cohorts.

  • 5

    Disease phenotype progression was lower in elderly-onset Crohn's disease and ulcerative colitis, indicating a different disease course compared to younger patients.

Original Source(s)

Inflammatory bowel diseases in the elderly population: epidemiology, long-term disease course, surgery rates, and biological use—data from the Veszprem county cohort between 1977 and 2020

  • by Dorottya Angyal, Lorant Gonczi, Fruzsina Balogh, Panu Wetwittayakhlang, Petra A Golovics, Tunde Pandur, Gyula David, Zsuzsanna Erdelyi, Istvan Szita, Akos Ilias, Laszlo Lakatos, Peter L Lakatos

  • January 6, 2025

Related Content

Urologic malignancy risk with chronic tumor necrosis factor-alpha inhibitor (TNF-I) exposure: a multicenter, retrospective cohort study

Curbing Drug-Related Halitosis for Closer Moments

Individuals who have drug-related halitosis may need to take additional steps to prioritize oral health before intimate encounters.

Strategies for Organ Regeneration Using Cell Therapy