Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children and Factors Influencing Fluconazole Resistance: A 15-Year Retrospective Cohort Study - Takeaways - MDSpire

Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children and Factors Influencing Fluconazole Resistance: A 15-Year Retrospective Cohort Study

  • By

  • Zumrut Sahbudak Bal

  • Sema Yildirim Arslan

  • Gizem Guner Ozenen

  • Gülizar Turan

  • Kübra Cebeci

  • Ulgen Celtik

  • Gulhadiye Avcu

  • Nihal Karadas

  • Gulcihan Ozek

  • Miray Karakoyun

  • Dilek Yesim Metin

  • Suleyha Hilmioglu Polat

  • January 8, 2026

  • 0 min

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  • 1

    Candidemia caused by Candida parapsilosis has become increasingly prevalent, particularly in pediatric populations.

  • 2

    Fluconazole resistance in C. parapsilosis has reached alarming rates of over 40-60% in some regions, complicating treatment.

  • 3

    The study analyzed 15 years of candidemia cases at Ege University Children’s Hospital, focusing on risk factors and clinical outcomes.

  • 4

    Identifying clinical risk factors for fluconazole resistance is crucial for guiding empirical therapy in pediatric patients.

  • 5

    The research highlights the need for further studies on C. parapsilosis to improve understanding and management of candidemia.

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