Modality-specific effects of structured exercise on immunometabolic biomarkers in postmenopausal obesity: a Bayesian network meta-analysis - Takeaways - MDSpire

Modality-specific effects of structured exercise on immunometabolic biomarkers in postmenopausal obesity: a Bayesian network meta-analysis

  • By

  • Gang Huang

  • Wang Wang

  • Hongyu Jiang

  • Bojun Zhu

  • Jiangfu Zhang

  • Zhixiong Chen

  • Peng Zhao

  • April 30, 2026

  • 0 min

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  • 1

    The study evaluates the efficacy of aerobic training, resistance training, high-intensity interval training, and combined training on inflammation biomarkers.

  • 2

    Resistance training showed the largest reduction in systemic C-reactive protein, while combined training was most effective in reducing interleukin-6 and tumor necrosis factor-α.

  • 3

    The analysis included 39 randomized controlled trials with 2,714 postmenopausal women, highlighting biomarker-specific adaptations to different exercise modalities.

  • 4

    Systemic leptin levels remained unchanged, indicating that exercise alone may not reverse hyperleptinemia in this population.

  • 5

    The overall certainty of evidence was rated low to very low, suggesting cautious interpretation of the exercise modality-specific efficacies.

Original Source(s)

Modality-specific effects of structured exercise on immunometabolic biomarkers in postmenopausal obesity: a Bayesian network meta-analysis

  • by Gang Huang, Wang Wang, Hongyu Jiang, Bojun Zhu, Jiangfu Zhang, Zhixiong Chen, Peng Zhao

  • April 30, 2026

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