Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis - Takeaways - MDSpire

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

  • By

  • Xinrui Yin

  • Shijia Du

  • June 5, 2026

  • 0 min

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  • 1

    Postoperative pneumonia and pulmonary complications are significant adverse events following thoracic surgery.

  • 2

    Higher preoperative neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) are associated with increased postoperative pulmonary risk.

  • 3

    The systematic review included eight retrospective cohort studies with a total of 3,936 patients.

  • 4

    Continuous analyses indicated a twofold increase in pneumonia odds per one-unit increment in NLR.

  • 5

    The overall certainty of evidence regarding NLR and SII as prognostic markers was assessed as low to very low.

Original Source(s)

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

  • by Xinrui Yin, Shijia Du

  • June 5, 2026

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