Exploring the Impact of Malnutrition-Associated Symptom Groups on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy: A Network Analysis - Takeaways - MDSpire

Exploring the Impact of Malnutrition-Associated Symptom Groups on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy: A Network Analysis

  • By

  • Meng-Yu Hao

  • Feng-Yan Li

  • Su-Man Zhang

  • Yu-Xian Yang

  • Yu-Xi Xiong

  • Hang-Yu Wang

  • Yao Zhuang Chuah

  • Zi-Hang Chen

  • Ling-Xin Xu

  • Peng Sun

  • Jian Ji

  • Lecheng Jia

  • Hua Li

  • Yanfei Liu

  • Ying Sun

  • Jia-Wei Lv

  • Yan Li

  • Guan-Qun Zhou

  • February 13, 2026

  • 0 min

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  • 1

    Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia, with over 70% of global cases occurring in these regions.

  • 2

    Malnutrition is common in NPC patients undergoing radiotherapy, significantly impacting their symptom burden and quality of life.

  • 3

    Network analysis reveals that symptoms in cancer patients often co-occur and interact, forming clusters that may worsen patient outcomes.

  • 4

    This study aims to integrate symptom clusters, nutritional status, and quality of life in NPC patients undergoing radiotherapy.

  • 5

    Patient-reported outcomes are essential for capturing the subjective symptom burden and improving personalized supportive care in NPC.

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