Diagnosing and Treating Ocular Lymphoma
At the 2026 Retina World Congress meeting, Kapil Mishra, MD, explained how new diagnostic tools and treatment agents are refining management of PVRL.
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Primary vitreoretinal lymphoma (PVRL) often presents with floaters and blurred vision, resembling chronic uveitis.
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Definitive diagnosis of PVRL relies on vitreous biopsy, with multimodal imaging aiding clinical suspicion.
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Intravitreal methotrexate is the most common local therapy for PVRL, though rituximab is an alternative for those intolerant.
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Emerging treatments for PVRL include BTK inhibitors like ibrutinib and zanubrutinib, showing promise in early trials.
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Survival rates for PVRL have improved significantly over the past decades, with increasing therapeutic options available.
