Weight Trajectory Impacts Risk for 10 Distinct Cardiometabolic Diseases - Takeaways - MDSpire

Weight Trajectory Impacts Risk for 10 Distinct Cardiometabolic Diseases

  • By

  • Alison Z Swartz

  • Kathryn Wood

  • Eric Farber-Eger

  • Alexander Petty

  • Heidi J Silver

  • June 11, 2025

  • 0 min

Share

  • 1

    Weight cycling significantly increases the risk for various cardiometabolic diseases compared to weight stability.

  • 2

    Weight cyclers face a 30% higher risk for obstructive sleep apnea, metabolic dysfunction-associated liver disease, and type 2 diabetes.

  • 3

    Heart failure risk is over 50% higher in weight cyclers, with both weight gain and loss also contributing to increased risk.

  • 4

    The study utilized electronic health records from Vanderbilt University Medical Center to analyze weight trajectories and disease risk.

  • 5

    Promoting weight stability or sustainable weight loss is crucial for preventing cardiometabolic diseases in individuals with high BMI.

Original Source(s)

Weight Trajectory Impacts Risk for 10 Distinct Cardiometabolic Diseases

  • by Alison Z Swartz, Kathryn Wood, Eric Farber-Eger, Alexander Petty, Heidi J Silver

  • June 11, 2025

Related Content

Association between region-specific epicardial adipose tissue and CT-derived fractional flow reserve-defined myocardial ischemia: a retrospective coronary CTA study stratified by hypertension and type 2 diabetes mellitus

Editorial: Interplay between glucose and lipid homeostasis in metabolic health

A machine learning model for diabetic retinopathy risk stratification using routine blood and urine parameters: insights into kidney-eye crosstalk