Polypharmacy and Activities of Daily Living in Older Patients Undergoing Cerebrovascular Rehabilitation: An Observational Study Using Japanese Real-World Data - Takeaways - MDSpire
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Polypharmacy and Functional Independence in Older Adults Receiving Cerebrovascular Rehabilitation: An Observational Study of Japanese Real-World Data

  • By

  • Yukari Ogawa

  • Takeshi Horii

  • Masaharu Sakoh

  • Kiyoshi Mihara

  • October 12, 2026

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  • 1

    This retrospective observational study used Japanese multicenter claims data to examine older adults receiving convalescent rehabilitation for cerebrovascular disease.

  • 2

    Polypharmacy was defined as use of 6 or more medications, and patients were grouped by polypharmacy status at admission and discharge.

  • 3

    The primary outcome was FIM gain, calculated as the difference between discharge and admission scores.

  • 4

    FIM gain was not significantly associated with polypharmacy status.

  • 5

    Compared with persistent non-polypharmacy, all 3 polypharmacy groups had lower FIM efficiency and longer hospital stays.

Original Source(s)

Polypharmacy and Activities of Daily Living in Older Patients Undergoing Cerebrovascular Rehabilitation: An Observational Study Using Japanese Real-World Data

  • by Yukari Ogawa, Takeshi Horii, Masaharu Sakoh, Kiyoshi Mihara

  • October 12, 2026

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