Misdiagnosis analysis and multidisciplinary collaborative treatment of primary cutaneous diffuse large B-cell lymphoma: case report

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Primary cutaneous diffuse large B-cell lymphoma (PC-DLBCL) is a rare non-Hodgkin lymphoma subtype often misdiagnosed due to nonspecific skin symptoms.
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An 85-year-old male patient experienced multiple misdiagnoses, leading to severe ulcerative skin lesions and requiring orthopedic intervention.
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The patient underwent multidisciplinary management, including orthopedic debridement, autologous skin grafting, and R-miniCHOP immunochemotherapy.
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Pathological examination confirmed the diagnosis of PC-DLBCL, emphasizing the importance of early biopsy for accurate diagnosis.
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The case highlights the necessity of multidisciplinary collaboration in managing advanced ulcerative PC-DLBCL to improve patient outcomes.

Frontiers In Medicine

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