Discrimination of benign and malignant ovarian sex cord-stromal tumors through the analysis of clinical features, MR imaging, and MR-based radiomics - Takeaways - MDSpire

Discrimination of benign and malignant ovarian sex cord-stromal tumors through the analysis of clinical features, MR imaging, and MR-based radiomics

  • By

  • Shifang Tan

  • Lingjie Zhang

  • Zhexuan Yang

  • Xueyan Liu

  • Meiying Cheng

  • Mingsheng Yi

  • Honglei Shang

  • Zhanqi Feng

  • Jingxu Xu

  • Chencui Huang

  • Xiaoan Zhang

  • Xin Zhao

  • May 25, 2026

  • 0 min

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  • 1

    The study involved 113 patients with 123 pathologically confirmed ovarian sex cord-stromal tumors, including 42 malignant and 81 benign cases.

  • 2

    Traditional models achieved the highest AUCs of 0.880 in training and 0.908 in validation for differentiating SCSTs.

  • 3

    The radiomics-based T2&DWI model reached AUCs of 0.887 in training and 0.843 in validation, indicating significant diagnostic potential.

  • 4

    The combined nomogram integrating clinical, MRI, and radiomic data demonstrated optimal predictive performance with AUCs of 0.945 and 0.914.

  • 5

    Decision curve analysis confirmed the combined model's greater clinical net benefit compared to traditional and radiomics models.

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