Predictive value of the uric acid-to-albumin ratio for contrast-induced nephropathy after percutaneous coronary intervention and construction of a clinical prediction model in patients with coronary artery disease - Takeaways - MDSpire

Predictive value of the uric acid-to-albumin ratio for contrast-induced nephropathy after percutaneous coronary intervention and construction of a clinical prediction model in patients with coronary artery disease

  • By

  • Yuxin Zhu

  • Qian Liu

  • Yun Deng

  • Jinfeng Chen

  • Yunxian Chen

  • Baofeng Chen

  • May 21, 2026

  • 0 min

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  • 1

    The study evaluated the uric acid-to-albumin ratio (UAR) as a predictor of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI).

  • 2

    CIN occurred in 9.6% of the 788 patients studied, highlighting its prevalence as a serious complication following PCI procedures.

  • 3

    UAR was identified as the strongest single predictor of CIN, with an odds ratio of 1.64, significantly enhancing pre-procedural risk stratification.

  • 4

    Incorporating UAR into a clinical prediction model improved the area under the ROC curve from 0.850 to 0.921, demonstrating its predictive value.

  • 5

    The study concluded that UAR is a novel predictor of CIN, warranting external validation before its widespread clinical implementation.

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