Acute Respiratory Infections Due to Antibiotic-nonsusceptible Streptococcus pneumoniae in US Adults - Takeaways - MDSpire

Acute Respiratory Infections Due to Antibiotic-nonsusceptible Streptococcus pneumoniae in US Adults

  • By

  • Laura M King

  • Kristin L Andrejko

  • Miwako Kobayashi

  • Wei Xing

  • Adam L Cohen

  • Joseph A Lewnard

  • January 7, 2026

  • 0 min

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  • 1

    Antibiotic-nonsusceptible Streptococcus pneumoniae significantly impacts acute respiratory infections in US adults.

  • 2

    An estimated 16.4% of nonbacteremic pneumonia and 19.0% of sinusitis cases are nonsusceptible to three or more antibiotic classes.

  • 3

    High proportions of pneumococcal pneumonia and sinusitis cases show nonsusceptibility to first-line outpatient antibiotics.

  • 4

    New pneumococcal conjugate vaccines (PCV15, PCV20, PCV21) are recommended to reduce antibiotic-nonsusceptible infections.

  • 5

    Understanding antibiotic-nonsusceptibility in pneumococcal infections is crucial for improving treatment and patient outcomes.

Original Source(s)

Acute Respiratory Infections Due to Antibiotic-nonsusceptible Streptococcus pneumoniae in US Adults

  • by Laura M King, Kristin L Andrejko, Miwako Kobayashi, Wei Xing, Adam L Cohen, Joseph A Lewnard

  • January 7, 2026

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