Incidence and outcome of salvage cystectomy after bladder sparing therapy for muscle invasive bladder cancer: a systematic review and meta-analysis - Takeaways - MDSpire

Incidence and outcome of salvage cystectomy after bladder sparing therapy for muscle invasive bladder cancer: a systematic review and meta-analysis

  • By

  • Victor M. Schuettfort

  • Benjamin Pradere

  • Fahad Quhal

  • Hadi Mostafaei

  • Ekaterina Laukhtina

  • Keiichiro Mori

  • Reza Sari Motlagh

  • Margit Fisch

  • David D’Andrea

  • Michael Rink

  • Paolo Gontero

  • Francesco Soria

  • Shahrokh F. Shariat

  • September 29, 2020

  • 0 min

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  • 1

    Bladder sparing therapy (BST) can provide oncologic outcomes comparable to radical cystectomy (RC) for selected muscle-invasive bladder cancer patients.

  • 2

    The most effective BST strategy involves maximal transurethral resection of bladder tumor followed by radiochemotherapy.

  • 3

    A significant number of patients may require salvage radical cystectomy (SV-RC) due to non-response to BST or local recurrence.

  • 4

    Complications after SV-RC are more likely due to the fragility of irradiated tissues, impacting patient outcomes.

  • 5

    The systematic review aimed to evaluate surgical and oncologic outcomes following SV-RC after BST, focusing on incidence rates and associated variables.

Original Source(s)

Incidence and outcome of salvage cystectomy after bladder sparing therapy for muscle invasive bladder cancer: a systematic review and meta-analysis

  • by Victor M. Schuettfort, Benjamin Pradere, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Reza Sari Motlagh, Margit Fisch, David D’Andrea, Michael Rink, Paolo Gontero, Francesco Soria, Shahrokh F. Shariat

  • September 29, 2020

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