Intestinal metastases diffused from primary gastric adenocarcinoma with signet ring cells: case report - Takeaways - MDSpire

Intestinal metastases diffused from primary gastric adenocarcinoma with signet ring cells: case report

  • By

  • Haiping Qi

  • Weiyan Li

  • Xingting Luo

  • Bin Huang

  • Xiaoguang Shi

  • Xuhua Xiao

  • July 13, 2026

Share

  • 1

    Signet ring cell carcinoma (SRCC) is a poorly differentiated subtype of gastric adenocarcinoma with a high propensity for metastasis.

  • 2

    This case report details a 62-year-old man with gastric SRCC exhibiting multiple polypoid intestinal metastases and elevated serum CEA levels.

  • 3

    Endoscopic evaluations revealed numerous ulcerative and polypoid lesions in the stomach, duodenum, and colorectum, confirmed as metastases.

  • 4

    Histopathological examination indicated poorly differentiated adenocarcinoma with signet ring cell features, affecting multiple intestinal sites.

  • 5

    The case highlights the unusual metastatic patterns of gastric SRCC and the importance of thorough assessments to avoid misdiagnosis.

Original Source(s)

Intestinal metastases diffused from primary gastric adenocarcinoma with signet ring cells: case report

  • by Haiping Qi, Weiyan Li, Xingting Luo, Bin Huang, Xiaoguang Shi, Xuhua Xiao

  • July 13, 2026

Related Content

One-carbon metabolism in cancer immunity: T-cell fitness, epigenetic programming, and therapeutic opportunities

KRAS G12C inhibitors in KRASG12C-mutated solid tumors: an immunologically informed systematic review and reconstructed individual patient data meta-analysis

Recombinant adenoviruses application for cancer vaccines: from genetic design to clinical translation