Migraine phenotypes defined by disability, pain topography and autonomic features: association with serum vitamin D status - Takeaways - MDSpire

Migraine phenotypes defined by disability, pain topography and autonomic features: association with serum vitamin D status

  • By

  • Majed Mohammad Alabdali

  • July 8, 2026

  • 0 min

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  • 1

    The study identified four distinct migraine phenotypes using cluster analysis based on clinical features and serum vitamin D levels.

  • 2

    Vitamin D deficiency was prevalent among migraine patients, with 67.4% having levels below 20 ng/mL, similar to general population estimates.

  • 3

    The left-sided aura-rich cluster exhibited the lowest median vitamin D levels at 9.54 ng/mL among the identified migraine phenotypes.

  • 4

    Female sex was a significant predictor of severe migraine phenotype membership, with an odds ratio of 3.37.

  • 5

    Differences in vitamin D levels across migraine phenotypes did not reach statistical significance, indicating a need for further investigation.

Original Source(s)

Migraine phenotypes defined by disability, pain topography and autonomic features: association with serum vitamin D status

  • by Majed Mohammad Alabdali

  • July 8, 2026

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