Navigating the Intersection of Infection and Cancer: Addressing Tuberculosis in Migrant Populations – A Case Study and Epidemiological Review

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Patients with hematologic malignancies are at increased risk for tuberculosis (TB) reactivation during immunosuppressive therapy.
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A case study highlights a refugee with Langerhans cell histiocytosis who developed TB during chemotherapy, emphasizing the need for awareness.
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Epidemiological data indicate rising TB cases among foreign-born patients in Germany, necessitating enhanced screening and diagnostic efforts.
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Molecular diagnostics are important, but culture remains a sensitive method for detecting Mycobacterium tuberculosis.
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The patient successfully underwent a modified TB treatment regimen after experiencing drug intolerance, leading to full regression of TB-affected lymph nodes.

Bmc Infectious Diseases

by Hans-Jörg Epple, Teresa Domaszewska, Ann-Christin von Brünneck, Christian Furth, Steffen Dommerich, Christoph Lange, Dinah von Schöning, Georg Maschmeyer, Lena Bös, Stefan Schwartz, Thomas Schneider, Stephan Mathas
December 23, 2025

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