Impact of AI-Assisted Endoscopy on Secondary Review and Referral Decisions in Gastric Cancer Screening: A Multicenter Real-World Study - Takeaways - MDSpire
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Effects of AI-Assisted Endoscopy on Secondary Image Review and Referral Decisions in Gastric Cancer Screening: A Multicenter Real-World Study

  • By

  • Sachiyo Onishi

  • Seiji Adachi

  • Masahito Shimizu

  • October 15, 2026

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  • 1

    This retrospective multicenter study compared secondary-review outcomes before and after AI-assisted endoscopy was introduced in a mobile gastric cancer screening program in Gifu, Japan.

  • 2

    The cohort included 5013 screening examinations: 2021 in 2021–2022 before AI implementation and 2992 in 2023–2025 during AI use.

  • 3

    During the AI period, primary endoscopists used real-time CADe alerts, but they retained responsibility for interpretation and referral decisions.

  • 4

    The structured secondary review process remained unchanged across study periods and involved independent review of recorded images and reports before referral was finalized.

  • 5

    Secondary-review modifications were descriptive process outcomes, not measures of diagnostic accuracy or clinical benefit, because no external reference standard was available.

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