Epicardial adipose tissue in cardiovascular diseases: a potential therapeutic target - Takeaways - MDSpire

Epicardial adipose tissue in cardiovascular diseases: a potential therapeutic target

  • By

  • Zhaoting Gong

  • Yuyan Xiong

  • June 18, 2026

  • 0 min

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  • 1

    Epicardial adipose tissue (EAT) is located between the myocardium and visceral pericardium, distinguishing it from other visceral adipose tissues.

  • 2

    EAT is associated with cardiovascular diseases (CVDs) and is being explored as a therapeutic target due to its unique secretomic profile.

  • 3

    EAT plays a dual role, providing cardioprotective effects under physiological conditions while promoting inflammation and fibrosis under pathological conditions.

  • 4

    Various imaging techniques, including echocardiography, CT, and MRI, are used to assess EAT and evaluate its relationship with CVD risk.

  • 5

    EAT-derived extracellular vesicles may contribute to CVD progression, highlighting EAT's potential as both a biomarker and a therapeutic target.

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