UC Irvine awarded $18 million to lead groundbreaking dementia study

UCI MIND secures major NIH funding to pioneer research into LATE, a common but underrecognized brain disease affecting older adults.

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UC Irvine's UCI MIND received an $18 million grant to lead a study on limbic predominant age-related TDP-43 encephalopathy (LATE).
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LATE is a neurodegenerative disease affecting up to 40% of older adults and mimics Alzheimer's but has a distinct pathology.
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The study aims to establish the first trial-ready cohort for LATE, recruiting participants aged 85 and older from five Alzheimer’s Disease Research Centers.
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Participants will undergo various assessments, including MRIs, blood draws, PET scans, and remote cognitive tests to identify biomarkers.
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This grant reinforces UC Irvine's leadership in dementia research and its commitment to improving brain health across diverse populations.

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