What Are the Latest Advances in Cholangiocarcinoma Treatment?

Cholangiocarcinoma, or bile duct cancer, is one of the most difficult cancers to diagnose and treat.

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Cholangiocarcinoma is difficult to detect early because it often causes no symptoms until advanced stages and has no known biomarkers for screening.
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Only about 20% to 30% of patients are eligible for surgical resection, and fewer than 5% qualify for liver transplantation.
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Liver transplantation may be an option for selected patients with small, unresectable tumors localized to the liver and no metastases.
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For advanced or metastatic bile duct cancer, first-line treatment now combines chemotherapy with immunotherapy.
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Molecular profiling identifies tumor mutations that can guide precision therapies, which may help treat inoperable disease.

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