Dana-Farber Research News 04.01.2026 - Takeaways - MDSpire
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Dana-Farber Research News 04.01.2026

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  • April 1, 2026

  • 37 min

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  • 1

    MTAP loss is common in oncogene-driven NSCLC, particularly in ALK-, RET-, and EGFR-altered subtypes.

  • 2

    BMS-986504 shows significant activity in MTAP-deleted NSCLC models, enhancing targeted therapy efficacy.

  • 3

    Nivolumab plus ipilimumab demonstrates long-term survival benefits in advanced renal cell carcinoma compared to sunitinib.

  • 4

    The CheckMate 214 trial reports a 9.3-year follow-up, showing lower treatment-related adverse events with NIVO+IPI.

  • 5

    Orca-T graft manipulation improves chronic GVHD-free survival in HLA-matched transplants compared to conventional grafts.

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